1. Yao L, Yang P, Luo W, Li S, Wu Y, Cai N, Bi D, Li H, Han Q, Xu X*. Macrophage-stimulating activity of European eel (Anguilla anguilla) peptides in RAW264.7 cells mediated via NF-κB and MAPK signaling pathways. Food & Function 2020, 11(12), 10968-10978.
2. Bi D, Yao L, Lin Z, Chi L, Li Hui, Xu H, Du X, Liu Q, Hu Z, Lu J, Xu X*. Unsaturated mannuronate oligosaccharide ameliorates β-amyloid pathology through autophagy in Alzheimer’s disease cell models. Carbohydrate Polymers 2021, 251: 117124.
3. Cai N, Luo W, Yao L, Li X, Wang Z, Xu H, Li H, Hu Z, Bao W, Xu X*. Activation of murine RAW264.7 macrophages by oligopeptides from sea cucumber (Apostichopus japonicus) and its molecular mechanisms. Journal of Functional Foods 2020, 75: 104229.
4. Yu B, Bi D, Yao L, Li T, Gu L, Xu H, Li X, Li H, Hu Z, Xu X*. The inhibitory activity of alginate against allergic reactions in an ovalbumin-induced mouse model. Food & Function 2020, 11(3): 2704-2713.
5. Bi D, Li X, Li T, Li X, Lin Z, Yao L, Li H, Xu H, Hu Z, Zhang Z, Liu Q, Xu X*. Characterization and neuroprotection potential of seleno-polymannuronate. Frontiers in Pharmacology 2020, 11: 21.
6. Cai N, Chen J, Bi D, Gu L, Yao L, Li X, Li H, Xu H, Hu Z, Liu Q, Xu X*. Specific degradation of endogenous Tau protein and inhibition of Tau fibrillation by tanshinone IIA through the ubiquitin-proteasome pathway. Journal of Agricultural and Food Chemistry 2020, 68(7): 2054-2062.
7. Gu L, Cai N, Lyu Y, Yao L, Wang F, Xu H, Hu Z, Li H, Xu X*. γ‐Mangostin ameliorates free fatty acid-induced lipid accumulation via the SIRT1/LKB1/AMPK pathway in HepG2 and L02 cells. Journal of Agricultural and Food Chemistry 2019, 67(50): 13929-13938.
8. Bi D, Lai Q, Liao X, Cai N, Li T, Fang W, Han Q, Yu B, Lin L, Xu H, Hu Z, Xu X*. Neuroimmunoregulatory potential of seleno-polymannuronate derived from alginate in lipopolysaccharide-stimulated BV2 microglia. Food Hydrocolloids 2019, 87: 925-932.
9. Bi D, Lai Q, Han Q, Cai N, He H, Fang W, Yi J, Li X, Xu H, Li X, Hu Z, Liu Q, Xu X*. Seleno-polymannuronate attenuates neuroinflammation by suppressing microglial and astrocytic activation. Journal of Functional Foods 2018, 51: 113-120.
10. Bi D, Yu B, Han Q, Lu J, White W, Lai Q, Cai N, Luo W, Gu L, Li S, Xu H, Hu Z, Nie S, Xu X*. Immune activation of RAW264.7 macrophages by low molecular weight fucoidan extracted from New Zealand Undaria pinnatifida. Journal of Agricultural and Food Chemistry 2018, 66(41): 10721-10728.
11. Bi D, Lai Q, Cai N, Li T, Zhang Y, Han Q, Peng Y, Xu H, Lu J, Bao W, Liu Q, Xu X*. Elucidation of the molecular-mechanisms and in vivo evaluation of the anti-inflammatory effect of alginate-derived seleno-polymannuronate. Journal of Agricultural and Food Chemistry 2018, 66(9): 2083-2091.
12. Bi D, Zhou R, Cai N, Lai Q, Han Q, Jiang Z, Tang Z, Peng Y, Lu J, Bao W, Xu H, Xu X*. Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages. International Journal of Biological Macromolecules 2017, 105(2): 1446-1454.
13. Fang W, Bi D, Zheng R, Cai N, Xu H, Zhou R, Lu J, Wan M, Xu X*. Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages. Scientific Reports 2017, 7(1): 1663.
14. Xu X, Bi D, Wan M. Characterization and immunological evaluation of low-molecular-weight alginate derivatives. Current Topics in Medicinal Chemistry 2016, 16(8): 874-887.
15. Zhou R, Shi X, Bi D, Fang W, Wei G, Xu X*. Alginate-derived oligosaccharide inhibits neuroinflammation and promotes microglial phagocytosis of β-amyloid. Marine Drugs 2015, 13(9): 5828-5846.
16. Xu X, Bi D, Li C, Fang W, Zhou R, Li S, Chi L, Wan M, Shen L. Morphological and proteomic analyses reveal that unsaturated guluronate oligosaccharide modulates multiple functional pathways in murine macrophage RAW264.7 cells. Marine Drugs 2015, 13(4): 1798-1818.
17. Zhou R, Shi X, Gao Y, Cai N, Jiang Z, Xu X*. Anti-inflammatory activity of guluronate oligosaccharides obtained by oxidative degradation from alginate in lipopolysaccharide-activated murine macrophage RAW 264.7 cells. Journal of Agricultural and Food Chemistry 2015, 63(1): 160-168.
18. Xu X, Bi D, Wu X, Wang Q, Wei G, Chi L, Jiang Z, Oda T, Wan M. Unsaturated guluronate oligosaccharide enhances the antibacterial activities of macrophages. The FASEB Journal 2014, 28(6): 2645-2654.
19. Xu X, Wu X, Wang Q, Cai N, Zhang H, Jiang Z, Wan M, Oda T. Immunomodulatory effects of alginate oligosaccharides on murine macrophage RAW264.7 cells and their structure-activity relationships. Journal of Agricultural and Food Chemistry 2014, 62(14): 3168-3176.
